Copy Number Variation on Chromosome 10q26.3 for Obesity Identified by a Genome-Wide Study
Author(s) -
TieLin Yang,
Yan Guo,
Hui Shen,
Jian Li,
Joseph Glessner,
Chuan Qiu,
FeiYan Deng,
Qing Tian,
Ping Yu,
Yaozhong Liu,
Yongjun Liu,
Hákon Hákonarson,
Struan F.A. Grant,
HongWen Deng
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2751
Subject(s) - obesity , copy number variation , body mass index , heritability , missing heritability problem , genetics , genome wide association study , biology , medicine , gene , endocrinology , genome , single nucleotide polymorphism , genotype
Obesity is a highly heritable disease defined by high body mass index (BMI). However, a large proportion of the heritability of obesity remains unexplained. Copy number variations (CNVs) might contribute to the missing heritability of obesity.
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