Diurnal Cortisol Changes in Newborn Infants Suggesting Entrainment of Peripheral Circadian Clockin Uteroand at Birth | Zendy

Osuke Iwata | Zendy; Hisayoshi Okamura | Zendy; Hiroki Saitsu | Zendy; Mamoru Saikusa | Zendy; Hiroshi Kanda | Zendy; Nobuoki Eshima | Zendy; Sachiko Iwata | Zendy; Yasuki Maeno | Zendy; Toyojiro Matsuishi | Zendy

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Diurnal Cortisol Changes in Newborn Infants Suggesting Entrainment of Peripheral Circadian Clockin Uteroand at Birth

Author(s) -

Osuke Iwata,

Hisayoshi Okamura,

Hiroki Saitsu,

Mamoru Saikusa,

Hiroshi Kanda,

Nobuoki Eshima,

Sachiko Iwata,

Yasuki Maeno,

Toyojiro Matsuishi

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2750

Subject(s) - circadian rhythm , entrainment (biomusicology) , endocrinology , medicine , rhythm , period (music) , circadian clock , saliva , glucocorticoid , hydrocortisone , in utero , fetus , biology , pregnancy , physics , acoustics , genetics

In the rodent and human fetus, a diurnal cortisol rhythm is observed that is entrained in antiphase to the maternal rhythm. However, after birth, the adrenal circadian rhythm becomes unsynchronized with the clock time, and an adult-type, 24-h rhythm is observed only after a few months. Little is known about when and how the fetal adrenal circadian rhythm is synchronized with the day-night cycle.

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