PCOS Is Associated with Increased CD11c Expression and Crown-Like Structures in Adipose Tissue and Increased Central Abdominal Fat Depots Independent of Obesity
Author(s) -
Zhihua Huang,
Buvana Manickam,
Victoria Ryvkin,
Xiaohong Joe Zhou,
Giamila Fantuzzi,
Theodore Mazzone,
Susan Sam
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2697
Subject(s) - adipose tissue , adiponectin , insulin resistance , medicine , endocrinology , abdominal obesity , body mass index , polycystic ovary , obesity , metabolic syndrome
Adipose tissue macrophage (ATM) infiltration is a major pathway for obesity-induced insulin resistance but has not been studied as a mechanism for insulin resistance in PCOS.
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