Prognostic Implications of miR-146b Expression and Its Functional Role in Papillary Thyroid Carcinoma | Zendy

ChenKai Chou | Zendy; Kuender D. Yang | Zendy; FongFu Chou | Zendy; ChaoCheng Huang | Zendy; Yueh-Wen Lan | Zendy; Ya-Fang Lee | Zendy; HongYo Kang | Zendy; RueTsuan Liu | Zendy

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Prognostic Implications of miR-146b Expression and Its Functional Role in Papillary Thyroid Carcinoma

Author(s) -

ChenKai Chou,

Kuender D. Yang,

FongFu Chou,

ChaoCheng Huang,

Yueh-Wen Lan,

Ya-Fang Lee,

HongYo Kang,

RueTsuan Liu

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2666

Subject(s) - thyroid carcinoma , microrna , medicine , chemotherapy , cancer research , apoptosis , metastasis , oncology , carcinoma , cancer , biology , endocrinology , pathology , thyroid , gene , biochemistry

Recent studies suggest that miR-146b deregulation in papillary thyroid carcinoma (PTC) was associated with advanced tumor characteristics. However, the influence of miR-146b expression on the prognosis of PTC remains unknown. We sought to correlate tumor expression levels of miR-146b with the prognosis of a previously reported PTC cohort and reveal the underlying mechanisms via a PTC cell line model.

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