Evidence for Chromosome 2p16.3 Polycystic Ovary Syndrome Susceptibility Locus in Affected Women of European Ancestry | Zendy

Priscilla Mutharasan | Zendy; Eugene Galdones | Zendy; Beatriz Peñalver Bernabé | Zendy; Obed Garcia | Zendy; Nadereh Jafari | Zendy; Lonnie D. Shea | Zendy; Teresa K. Woodruff | Zendy; Richard S. Legro | Zendy; Andrea Dunaif | Zendy; Margrit Urbanek | Zendy

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Evidence for Chromosome 2p16.3 Polycystic Ovary Syndrome Susceptibility Locus in Affected Women of European Ancestry

Author(s) -

Priscilla Mutharasan,

Eugene Galdones,

Beatriz Peñalver Bernabé,

Obed Garcia,

Nadereh Jafari,

Lonnie D. Shea,

Teresa K. Woodruff,

Richard S. Legro,

Andrea Dunaif,

Margrit Urbanek

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2471

Subject(s) - polycystic ovary , locus (genetics) , single nucleotide polymorphism , genetics , haplotype , genetic association , genome wide association study , medicine , endocrinology , biology , cohort , gene , genotype , insulin resistance , obesity

A previous genome-wide association study in Chinese women with polycystic ovary syndrome (PCOS) identified a region on chromosome 2p16.3 encoding the LH/choriogonadotropin receptor (LHCGR) and FSH receptor (FSHR) genes as a reproducible PCOS susceptibility locus.

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