Growth Hormone Receptor (GHR) Exon 3 Polymorphism Status Detection by Dual-Enzyme-Linked Immunosorbent Assay (ELISA) | Zendy

JunXiang Wan | Zendy; Gil Atzmon | Zendy; David Hwang | Zendy; Nir Barzlai | Zendy; Jürgen Kratzsch | Zendy; Pinchas Cohen | Zendy

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Growth Hormone Receptor (GHR) Exon 3 Polymorphism Status Detection by Dual-Enzyme-Linked Immunosorbent Assay (ELISA)

Author(s) -

JunXiang Wan,

Gil Atzmon,

David Hwang,

Nir Barzlai,

Jürgen Kratzsch,

Pinchas Cohen

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2375

Subject(s) - growth hormone receptor , genotyping , genotype , exon , biology , microbiology and biotechnology , polymorphism (computer science) , medicine , immunoassay , endocrinology , single nucleotide polymorphism , antibody , immunology , genetics , growth hormone , gene , hormone

GH receptor (GHR) exon 3-deleted/full-length (d3/fl) polymorphism has been proposed to affect the responsiveness to GH therapy. Conventional multiplex PCR genotyping method for this polymorphism detection requires DNA samples, which may be difficult to obtain due to ethical and procedural issues and may limit further studies into the role of this polymorphism in health and disease.

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