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Low Circulating Adropin Concentrations with Obesity and Aging Correlate with Risk Factors for Metabolic Disease and Increase after Gastric Bypass Surgery in Humans
Author(s) -
Andrew A. Butler,
Charmaine S. Tam,
Kimber L. Stanhope,
Bruce M. Wolfe,
Mohamed R. Ali,
Majella O’Keeffe,
MariePierre StOnge,
Éric Ravussin,
Peter J. Havel
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2194
Subject(s) - medicine , insulin resistance , endocrinology , obesity , body mass index , overweight , confidence interval , gastric bypass surgery , weight loss , gastric bypass
Mouse studies suggest that adropin, a peptide hormone, is required for metabolic homeostasis and prevention of obesity-associated insulin resistance. Whether obesity and insulin resistance are associated with low plasma adropin levels in humans is not known.

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