Gender-Specific Alterations in Fibrin Structure Function in Type 2 Diabetes: Associations with Cardiometabolic and Vascular Markers
Author(s) -
Saad Alzahrani,
Katharina Heß,
Jackie F. Price,
Mark W. J. Strachan,
Paul D. Baxter,
Richard M. Cubbon,
Fladia Phoenix,
T Gamlen,
Robert A. S. Ariëns,
Peter J. Grant,
Ramzi Ajjan
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2128
Subject(s) - fibrinolysis , fibrinogen , medicine , fibrin , diabetes mellitus , endocrinology , odds ratio , plasminogen activator , body mass index , type 2 diabetes , plasminogen activator inhibitor 1 , thrombus , cardiology , immunology
Diabetes is associated with increased incidence of atherothrombotic disease. The fibrin network forms the backbone of the arterial thrombus, and fibrin clot structure determines predisposition to cardiovascular events.
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