Total and High-Molecular-Weight Adiponectin and Risk of Coronary Heart Disease and Ischemic Stroke in Older Adults | Zendy

Jorge R. Kizer | Zendy; David Benkeser | Zendy; Alice M. Arnold | Zendy; Luc Djoussé | Zendy; Susan J. Zieman | Zendy; Kenneth J. Mukamal | Zendy; Russell P. Tracy | Zendy; Christos S. Mantzoros | Zendy; David S. Siscovick | Zendy; John S. Gottdiener | Zendy; Joachim H. Ix | Zendy

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Total and High-Molecular-Weight Adiponectin and Risk of Coronary Heart Disease and Ischemic Stroke in Older Adults

Author(s) -

Jorge R. Kizer,

David Benkeser,

Alice M. Arnold,

Luc Djoussé,

Susan J. Zieman,

Kenneth J. Mukamal,

Russell P. Tracy,

Christos S. Mantzoros,

David S. Siscovick,

John S. Gottdiener,

Joachim H. Ix

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2103

Subject(s) - adiponectin , hazard ratio , medicine , confounding , prospective cohort study , confidence interval , stroke (engine) , cardiology , myocardial infarction , cohort study , proportional hazards model , cohort , endocrinology , obesity , insulin resistance , mechanical engineering , engineering

Adiponectin is atheroprotective in the laboratory, but prospective studies have shown opposite associations with cardiovascular disease (CVD) in healthy middle-aged populations (protective) and older cohorts (adverse). Whether this relates to different proportions of high-molecular-weight (HMW) adiponectin is unknown.

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