Negative Fetal FSH/LH Regulation in Late Pregnancy Is Associated with Declined Kisspeptin/KISS1R Expression in the Tuberal Hypothalamus | Zendy

Fabien Guimiot | Zendy; L. Chevrier | Zendy; Sophie Dreux | Zendy; Didier Chevenne | Zendy; Alain Caraty | Zendy; Anne Lise Delezoïde | Zendy; Nicolás de Roux | Zendy

Open Access

Negative Fetal FSH/LH Regulation in Late Pregnancy Is Associated with Declined Kisspeptin/KISS1R Expression in the Tuberal Hypothalamus

Author(s) -

Fabien Guimiot,

L. Chevrier,

Sophie Dreux,

Didier Chevenne,

Alain Caraty,

Anne Lise Delezoïde,

Nicolás de Roux

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2078

Subject(s) - kisspeptin , medicine , endocrinology , hypothalamus , gonadotropin releasing hormone , biology , arcuate nucleus , luteinizing hormone , median eminence , hormone

Kisspeptins were recently identified as hypothalamic neuropeptides that control GnRH release at pubertal onset and in adults via the activation of KISS-1 receptor (KISS1R). Here, we have tested whether the fetal activation of the gonadotropic axis is related to the hypothalamic expression of kisspeptins and KISS1R.

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