Ghrelin Stimulation of Growth Hormone Isoforms: Parallel Secretion of Total and 20-kDa Growth Hormone and Relation to Insulin Sensitivity in Healthy Humans | Zendy

Jenny Tong | Zendy; David A. D’Alessio | Zendy; Juliane Ramisch | Zendy; Harold W. Davis | Zendy; Elizabeth Stambrook | Zendy; Matthias H. Tschöp | Zendy; Martin Bidlingmaier | Zendy

Open Access

Ghrelin Stimulation of Growth Hormone Isoforms: Parallel Secretion of Total and 20-kDa Growth Hormone and Relation to Insulin Sensitivity in Healthy Humans

Author(s) -

Jenny Tong,

David A. D’Alessio,

Juliane Ramisch,

Harold W. Davis,

Elizabeth Stambrook,

Matthias H. Tschöp,

Martin Bidlingmaier

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2012

Subject(s) - medicine , endocrinology , ghrelin , insulin , basal (medicine) , hormone , glucose homeostasis , stimulation , biology , chemistry , insulin resistance

The 20-kDa human GH (hGH) is produced in the pituitary by alternative splicing of the hGH-N gene. The 20-kDa hGH promotes growth similarly to 22-kDa or total hGH, the predominant form in circulation, but the relative effects of these isoforms on glucose metabolism have been debated.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research