Circulating Osteogenic Precursor Cells in Type 2 Diabetes Mellitus
Author(s) -
John S. Manavalan,
Serge Cremers,
David W. Dempster,
Hua Zhou,
Elzbieta Dworakowski,
Aruna Kode,
Stavroula Kousteni,
Mishaela R. Rubin
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-1546
Subject(s) - type 2 diabetes mellitus , chemistry , diabetes mellitus , medicine , endocrinology , microbiology and biotechnology , biology
Type 2 diabetes mellitus (T2D) is associated with an increased risk of fractures and low bone formation. However, the mechanism for the low bone formation is not well understood. Recently, circulating osteogenic precursor (COP) cells, which contribute to bone formation, have been characterized in the peripheral circulation.
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