BRAFV600E Mutation Does Not Mean Distant Metastasis in Thyroid Papillary Carcinomas | Zendy

Valentina Sancisi | Zendy; Davide Nicoli | Zendy; Moira Ragazzi | Zendy; Simonetta Piana | Zendy; Alessia Ciarrocchi | Zendy

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BRAFV600E Mutation Does Not Mean Distant Metastasis in Thyroid Papillary Carcinomas

Author(s) -

Valentina Sancisi,

Davide Nicoli,

Moira Ragazzi,

Simonetta Piana,

Alessia Ciarrocchi

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-1526

Subject(s) - thyroid carcinoma , mutation , metastasis , distant metastasis , medicine , thyroid , cancer research , carcinoma , oncology , mutation frequency , cancer , pathology , biology , gene , genetics

The oncogenic BRAFV600E mutation has been frequently associated with aggressive behavior of papillary thyroid carcinomas. However, controversy exists on the consistency of these data, and very little is known about the relationship between this genetic alteration and the tendency of papillary thyroid carcinoma (PTC) to develop metastasis at distant sites.

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