A Multiinstitutional Phase 2 Trial of Pazopanib Monotherapy in Advanced Anaplastic Thyroid Cancer
Author(s) -
Keith C. Bible,
Vera J. Suman,
Michael E. Menefee,
Robert C. Smallridge,
Julian R. Molina,
William J. Maples,
Nina J. Karlin,
Anne M. Traynor,
Priya Kumar,
Boon Cher Goh,
WanTeck Lim,
Ayoko R. Bossou,
Crescent R. Isham,
Kevin Webster,
Andrea K. Kukla,
Carolyn Bieber,
Jill K. Burton,
Pamela Jo Harris,
Charles Erlichman
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-1520
Subject(s) - pazopanib , anaplastic thyroid cancer , medicine , oncology , thyroid cancer , phases of clinical research , cancer , clinical trial , sunitinib
Pazopanib, an inhibitor of kinases including vascular endothelial growth factor receptor, demonstrated impressive activity in progressive metastatic differentiated thyroid cancer, prompting its evaluation in anaplastic thyroid cancer (ATC).
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