Non-Nutritive Sweeteners and their Role in the Gastrointestinal Tract | Zendy

Rebecca J. Brown | Zendy; Kristina I. Rother | Zendy

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Non-Nutritive Sweeteners and their Role in the Gastrointestinal Tract

Author(s) -

Rebecca J. Brown,

Kristina I. Rother

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-1475

Subject(s) - hormone , enteroendocrine cell , secretion , endocrinology , taste , medicine , glucagon like peptide 1 , glucagon , gastrointestinal tract , ingestion , biology , gastrointestinal hormone , peptide hormone , endocrine system , food science , diabetes mellitus , type 2 diabetes

Non-nutritive sweeteners can bind to sweet-taste receptors present not only in the oral cavity, but also on enteroendocrine and pancreatic islet cells. Thus, these sweeteners may have biological activity by eliciting or inhibiting hormone secretion. Because consumption of non-nutritive sweeteners is common in the United States, understanding the physiological effects of these substances is of interest and importance.

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