Presence of Strong Association of the Major Histocompatibility Complex (MHC) Class I AlleleHLA-A*26:01with Idiopathic Hypoparathyroidism | Zendy

Ravinder Goswami | Zendy; Archana Singh | Zendy; Nandita Gupta | Zendy; Rajni Rani | Zendy

Open Access

Presence of Strong Association of the Major Histocompatibility Complex (MHC) Class I AlleleHLA-A*26:01with Idiopathic Hypoparathyroidism

Author(s) -

Ravinder Goswami,

Archana Singh,

Nandita Gupta,

Rajni Rani

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-1328

Subject(s) - human leukocyte antigen , major histocompatibility complex , allele , immunology , linkage disequilibrium , locus (genetics) , biology , genetics , haplotype , antigen , odds ratio , pathogenesis , medicine , gene

The pathogenesis of isolated hypoparathyroidism, also referred to as idiopathic hypoparathyroidism (IH), is not clear. There is a paucity of information related to the immunogenetic basis of the disease due to its rarity. A recurrent theme of several autoimmune disorders is aberrant antigen presentation.

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