Higher Levels of Endogenous Estradiol are Associated with Frailty in Postmenopausal Women from the Toledo Study for Healthy Aging
Author(s) -
Laure CarcaillonBentata,
Francisco J. GarcíaGarcía,
J. A. F. Tresguerres,
Guillermo Gutiérrez Avila,
Roman Kireev,
Leocadio Rodrı́guez-Mañas
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-1271
Subject(s) - medicine , odds ratio , confidence interval , body mass index , logistic regression , cohort study , frailty syndrome , cohort , population , endocrinology , gerontology , frailty index , environmental health
Adverse effects of higher endogenous estradiol (E2) levels on various clinical outcomes and on determinants of the frailty syndrome have recently been reported. However, there are no data about the potential relationship between E2 and frailty. We aimed to study the association between E2 levels and frailty among older postmenopausal women not taking hormonal therapy.
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