Biological Characteristics of Growth Hormone-Producing Pituitary Adenomas Are Different According to Responsiveness to Thyrotropin-Releasing Hormone | Zendy

Hideyuki Arita | Zendy; Manabu Kinoshita | Zendy; Satoru Oshino | Zendy; Tetsuhiro Kitamura | Zendy; Michio Otsuki | Zendy; Soji Kasayama | Zendy; Toshio Shimokawa | Zendy; Iichiro Shimomura | Zendy; Toshiki Yoshimine | Zendy; Youichi Saitoh | Zendy

Open Access

Biological Characteristics of Growth Hormone-Producing Pituitary Adenomas Are Different According to Responsiveness to Thyrotropin-Releasing Hormone

Author(s) -

Hideyuki Arita,

Manabu Kinoshita,

Satoru Oshino,

Tetsuhiro Kitamura,

Michio Otsuki,

Soji Kasayama,

Toshio Shimokawa,

Iichiro Shimomura,

Toshiki Yoshimine,

Youichi Saitoh

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-1125

Subject(s) - acromegaly , medicine , thyrotropin releasing hormone , endocrinology , basal (medicine) , cytokeratin , staining , pituitary tumors , hormone , trh stimulation test , immunohistochemistry , growth hormone , pathology , insulin

The paradoxical response of GH to TRH in patients with acromegaly has been previously reported. However, few reports have focused on tumor characteristics reflected by this response. This study aimed to clarify the relationship between TRH-induced GH responsiveness and other tumor characteristics.

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