Cardiovascular Benefits of Exogenous Insulin
Author(s) -
Ajay Chaudhuri,
Paresh Dandona,
Vivian Fonseca
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-1112
Subject(s) - medicine , insulin , context (archaeology) , myocardial infarction , glycemic , clinical trial , diabetes mellitus , hypoglycemia , proinflammatory cytokine , disease , intensive care medicine , endocrinology , inflammation , paleontology , biology
Recent studies on mediators of inflammation, experimental models of atherosclerosis, and acute ischemia have identified novel mechanisms through which insulin may exert cardiovascular protective effects. This review aims to summarize current knowledge regarding the cardiovascular, antiinflammatory, and antiatherogenic effects of insulin, and the effect of intensive glycemic control in acute cardiovascular disease.
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