Variants inDENND1AAre Associated with Polycystic Ovary Syndrome in Women of European Ancestry
Author(s) -
Corrine K. Welt,
Unnur Styrkársdóttir,
David A. Ehrmann,
Guðmar Þorleifsson,
G. Arason,
Jens A. Guðmundsson,
Carole Ober,
Robert L. Rosenfield,
Richa Saxena,
Unnur Þorsteinsdóttir,
William F. Crowley,
Kári Stéfansson
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-3478
Subject(s) - polycystic ovary , hyperandrogenism , odds ratio , gynecology , demography , medicine , genetics , biology , obesity , insulin resistance , sociology
A genome-wide association study has identified three loci (five independent signals) that confer risk for polycystic ovary syndrome (PCOS) in Han Chinese women. Replication is necessary to determine whether the same variants confer risk for PCOS in women of European ancestry.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom