Programmed Death-1+ T Cells and Regulatory T Cells Are Enriched in Tumor-Involved Lymph Nodes and Associated with Aggressive Features in Papillary Thyroid Cancer | Zendy

Jena D. French | Zendy; Gregory Kotnis | Zendy; Sherif Said | Zendy; Christopher D. Raeburn | Zendy; Robert C. McIntyre | Zendy; Joshua Klopper | Zendy; Bryan R. Haugen | Zendy

Open Access

Programmed Death-1+ T Cells and Regulatory T Cells Are Enriched in Tumor-Involved Lymph Nodes and Associated with Aggressive Features in Papillary Thyroid Cancer

Author(s) -

Jena D. French,

Gregory Kotnis,

Sherif Said,

Christopher D. Raeburn,

Robert C. McIntyre,

Joshua Klopper,

Bryan R. Haugen

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-3428

Subject(s) - lymph , papillary thyroid cancer , thyroid cancer , cancer research , pathology , cancer cell , tumor cells , medicine , cancer , biology

Recurrent metastatic lymph node (LN) disease is common in patients with papillary thyroid cancer (PTC). Novel prognostic markers may be helpful in guiding a therapeutic approach. Our previous studies revealed that immune suppression is evident in PTC and associated with more severe disease.

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