Orexigenic Neuropeptide 26RFa: New Evidence for an Adaptive Profile of Appetite Regulation in Anorexia Nervosa
Author(s) -
Émilie Fauquembergue,
Olivier Toutirais,
David Tougeron,
Aurélie Drouet,
Matthieu Le Gallo,
Mireille Desille,
Florian Cabillic,
Cécile Thomas de La Pintière,
Manuela Iero,
Licia Rivoltini,
Stéphanie BaertDesurmont,
Hubert Vaudry,
Richard Sesboüé,
Thierry Frébourg,
JeanBaptiste Latouche,
Véronique Catros,
Debbie Gach,
Djida Belkacemi,
R Lefranc,
D Perlikowski,
JeanMichel Masson,
R Walet-Balieu,
JeanLuc DoRégo,
R Galas,
Damien Schapman,
D Lamtahri,
David To,
David Vaudry,
Julien Chuquet,
Katarzyna Gach,
O. Belkacemi,
Benjamin Lefranc,
P. Perlikowski,
Marie-Laure Walet-Balieu,
Ludovic Galas,
Rhita Lamtahri,
M.C. To,
Bogdan Galusca,
Lydie Jeandel,
Natacha Germain,
David Alexandre,
Jérôme Leprince,
Youssef Anouar,
Bruno Estour,
Nicolas Chartrel
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-3396
Subject(s) - ghrelin , orexigenic , appetite , medicine , endocrinology , circadian rhythm , morning , evening , anorexia nervosa , neuropeptide y receptor , neuropeptide , hormone , eating disorders , psychiatry , physics , receptor , astronomy
Restrictive anorexia nervosa (AN) presents an adaptive appetite regulating profile including mainly high levels of ghrelin. Because this adaptive mechanism is not effective on food intake, other appetite-regulating peptides need to be explored. 26RFa is a hypothalamic neuropeptide that stimulates appetite, gonadotropin release, and bone metabolism.
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