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AgRP and NPY Expression in the Human Hypothalamic Infundibular Nucleus Correlate with Body Mass Index, Whereas Changes in αMSH Are Related to Type 2 Diabetes
Author(s) -
Anneke Alkemade,
ChunXia Yi,
Lei Pei,
Magdaléna Harakaľová,
Dick F. Swaab,
Susanne E. la Fleur,
Eric Fliers,
Andries Kalsbeek
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-3259
Subject(s) - endocrinology , medicine , neuropeptide y receptor , arcuate nucleus , hypothalamus , type 2 diabetes , body mass index , diabetes mellitus , neuropeptide , obesity , overweight , insulin resistance , nucleus , biology , receptor , neuroscience
Rodent data show that altered hypothalamic signaling contributes to the development of obesity and insulin resistance.

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