A High Prevalence of Dual Thyroid Ectopy in Congenital Hypothyroidism: Evidence for Insufficient Signaling Gradients during Embryonic Thyroid Migration or for the Polyclonal Nature of the Thyroid Gland? | Zendy

Stefanie Wildi-Runge | Zendy; Sophie StoppaVaucher | Zendy; Raymond Lambert | Zendy; Sophie Turpin | Zendy; Guy Van Vliet | Zendy; Johnny Deladoëy | Zendy

Open Access

A High Prevalence of Dual Thyroid Ectopy in Congenital Hypothyroidism: Evidence for Insufficient Signaling Gradients during Embryonic Thyroid Migration or for the Polyclonal Nature of the Thyroid Gland?

Author(s) -

Stefanie Wildi-Runge,

Sophie StoppaVaucher,

Raymond Lambert,

Sophie Turpin,

Guy Van Vliet,

Johnny Deladoëy

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-3156

Subject(s) - thyroid , congenital hypothyroidism , endocrinology , medicine , pathology

Thyroid ectopy results from the failure of the thyroid precursor cells to migrate from the primordial pharynx to the anterior part of the neck. Most ectopic thyroids are revealed by congenital hypothyroidism and present as a single round mass at the base of the tongue, with no other thyroid tissue. However, some cases have dual ectopy, with part of the tissue having partially migrated. We hypothesized that this occurs more frequently than previously reported.

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