Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta | Zendy

Wen Wang | Zendy; Lin Feng | Zendy; Honghai Zhang | Zendy; Stephanie Hachy | Zendy; Seiro Satohisa | Zendy; Louise C. Laurent | Zendy; Mana M. Parast | Zendy; Jing Zheng | Zendy; Dongbao Chen | Zendy

Open Access

Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta

Author(s) -

Wen Wang,

Lin Feng,

Honghai Zhang,

Stephanie Hachy,

Seiro Satohisa,

Louise C. Laurent,

Mana M. Parast,

Jing Zheng,

Dongbao Chen

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-3131

Subject(s) - microrna , angiogenesis , preeclampsia , placenta , ephrin , pregnancy , andrology , human placenta , medicine , cancer research , biology , microbiology and biotechnology , gene , genetics , fetus , signal transduction

Placental angiogenesis contributes to the pathogenesis of preeclampsia (PE) that affects 5-8% of all human pregnancies. MicroRNA (miRNA) are a class of noncoding 21- to 25-nucleotide RNA that negatively regulate gene expression posttranscriptionly.

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