Transforming Growth Factor β1 (TGFβ1) and Progesterone Regulate Matrix Metalloproteinases (MMP) in Human Endometrial Stromal Cells | Zendy

Hiroko Itoh | Zendy; A. Hari Kishore | Zendy; Annika Lindqvist | Zendy; David E. Rogers | Zendy; R. Ann Word | Zendy

Open Access

Transforming Growth Factor β1 (TGFβ1) and Progesterone Regulate Matrix Metalloproteinases (MMP) in Human Endometrial Stromal Cells

Author(s) -

Hiroko Itoh,

A. Hari Kishore,

Annika Lindqvist,

David E. Rogers,

R. Ann Word

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-3073

Subject(s) - stromal cell , mmp2 , matrix metalloproteinase , mmp9 , endocrinology , transforming growth factor , medicine , endometrium , decidualization , progesterone receptor , biology , chemistry , downregulation and upregulation , estrogen receptor , gene , biochemistry , cancer , breast cancer , metastasis

Menstruation is preceded by progesterone withdrawal and endometrial matrix remodeling predominantly through induction of matrix metalloproteinases (MMP) and recruitment of invading neutrophils.

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