Lymphocytic Thyroiditis on Histology Correlates with Serum Thyroglobulin Autoantibodies in Patients with Papillary Thyroid Carcinoma: Impact on Detection of Serum Thyroglobulin
Author(s) -
Francesco Latrofa,
Debora Ricci,
Lucia Montanelli,
Roberto Rocchi,
Paolo Piaggi,
Eleonora Sisti,
L. Grasso,
Fulvio Basolo,
Clara Ugolini,
Aldo Pinchera,
Paolo Vitti
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-2812
Subject(s) - medicine , thyroglobulin , thyroid carcinoma , thyroiditis , thyroid , endocrinology , autoantibody , gastroenterology , pathology , antibody , immunology
Serum thyroglobulin (Tg), the marker of residual tumor in papillary thyroid carcinoma, can be underestimated in patients with Tg autoantibodies (TgAb). TgAb are due to a coexistent lymphocytic thyroiditis (LT) or the papillary thyroid carcinoma per se. TgAb assays are highly discordant.
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