Quantitative High-Throughput Drug Screening Identifies Novel Classes of Drugs with Anticancer Activity in Thyroid Cancer Cells: Opportunities for Repurposing | Zendy

Lisa Zhang | Zendy; Mei He | Zendy; Ya-Qin Zhang | Zendy; Naris Nilubol | Zendy; Min Shen | Zendy; Electron Kebebew | Zendy

Open Access

Quantitative High-Throughput Drug Screening Identifies Novel Classes of Drugs with Anticancer Activity in Thyroid Cancer Cells: Opportunities for Repurposing

Author(s) -

Lisa Zhang,

Mei He,

Ya-Qin Zhang,

Naris Nilubol,

Min Shen,

Electron Kebebew

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-2671

Subject(s) - drug repositioning , repurposing , drug , cancer , drug discovery , thyroid cancer , pharmacology , computational biology , high throughput screening , cancer drugs , thyroid , throughput , medicine , biology , bioinformatics , computer science , ecology , telecommunications , wireless

Despite increased understanding of the pathogenesis and targets for thyroid cancer and other cancers, developing a new anticancer chemical agent remains an expensive and long process. An alternative approach is the exploitation of clinically used and/or bioactive compounds.

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