Link between Adipose Tissue Angiogenesis and Fat Accumulation in Severely Obese Subjects
Author(s) -
Amal Y. Lemoine,
Séverine Ledoux,
Isabelle Quéguiner,
Sophie Caldérari,
Charlotte Mechler,
Simon Msika,
Pierre Corvol,
Étienne Larger
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-2649
Subject(s) - angiogenesis , adipose tissue , medicine , endocrinology , adipocyte , insulin resistance , obesity , vascular endothelial growth factor , metabolic syndrome , neovascularization , biology , vegf receptors
White adipose tissue (WAT) can rapidly expand or regress under different nutritional conditions. The role of angiogenesis in the expandability of human adipose tissue is established. However, whether sc and omental WAT (scWAT and oWAT) angiogenesis could influence fat distribution and metabolic diseases is not known.
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