Runx2 mRNA Expression in the Tissue, Serum, and Circulating Non-Hematopoietic Cells of Patients with Thyroid Cancer | Zendy

Luca Dalle Carbonare | Zendy; Anna Chiara Frigo | Zendy; Giuseppe Francia | Zendy; Maria Vittoria Davì | Zendy; Luca Donatelli | Zendy; Chiara Stranieri | Zendy; Paolo Brazzarola | Zendy; Maria Chiara Zatelli | Zendy; Fabio Menestrina | Zendy; Maria Teresa Valenti | Zendy

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Runx2 mRNA Expression in the Tissue, Serum, and Circulating Non-Hematopoietic Cells of Patients with Thyroid Cancer

Author(s) -

Luca Dalle Carbonare,

Anna Chiara Frigo,

Giuseppe Francia,

Maria Vittoria Davì,

Luca Donatelli,

Chiara Stranieri,

Paolo Brazzarola,

Maria Chiara Zatelli,

Fabio Menestrina,

Maria Teresa Valenti

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-2624

Subject(s) - thyroid carcinoma , medicine , thyroid , thyroid cancer , papillary thyroid cancer , cancer , pathological , runx2 , haematopoiesis , pathology , cancer research , messenger rna , gene expression , stem cell , biology , gene , biochemistry , genetics

Runx2, a master gene of osteogenic differentiation, is also expressed in nonosseous cancer cells. Microcalcifications are characteristic of papillary thyroid carcinoma and represent a useful find for diagnosis. However, the molecular expression of osteogenic differentiation transcription factor Runx2 has been poorly investigated in this tumor.

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