Comparative Effects of Variations in Duodenal Glucose Load on Glycemic, Insulinemic, and Incretin Responses in Healthy Young and Older Subjects | Zendy

Laurence G. Trahair | Zendy; Michael Horowitz | Zendy; Christopher K. Rayner | Zendy; Diana Gentilcore | Zendy; Kylie Lange | Zendy; Judith M. Wishart | Zendy; Karen L. Jones | Zendy

Open Access

Comparative Effects of Variations in Duodenal Glucose Load on Glycemic, Insulinemic, and Incretin Responses in Healthy Young and Older Subjects

Author(s) -

Laurence G. Trahair,

Michael Horowitz,

Christopher K. Rayner,

Diana Gentilcore,

Kylie Lange,

Judith M. Wishart,

Karen L. Jones

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-2583

Subject(s) - incretin , medicine , endocrinology , glycemic , insulin , insulin resistance , glucose homeostasis , gastric emptying , impaired glucose tolerance , diabetes mellitus , glucagon , pancreatic hormone , type 2 diabetes , stomach

Aging is associated with deteriorating glucose tolerance. Studies assessing glucose tolerance and subsequent insulin and incretin hormone release often fail to take into account the rate of gastric emptying when evaluating these responses.

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