Effect of Type 2 Diabetes Predisposing Genetic Variants on Colorectal Cancer Risk
Author(s) -
Juan Sáinz,
Anja Rudolph,
Michael Hoffmeister,
Bernd Frank,
Hermann Brenner,
Jenny ChangClaude,
Kari Hemminki,
Asta Försti
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-2565
Subject(s) - tcf7l2 , type 2 diabetes , single nucleotide polymorphism , allele , snp , population , oncology , medicine , genome wide association study , body mass index , colorectal cancer , genetics , biology , cancer , diabetes mellitus , endocrinology , genotype , gene , environmental health
The link between colorectal cancer (CRC) and type 2 diabetes mellitus (T2D) has been extensively studied. Although it is commonly accepted that T2D is a risk factor for CRC, the underlying mechanisms are still poorly understood.
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