Defects in GLP-1 Response to an Oral Challenge Do Not Play a Significant Role in the Pathogenesis of Prediabetes
Author(s) -
Galina Smushkin,
Airani Sathananthan,
Chiara Dalla Man,
Alan R. Zinsmeister,
Michael Camilleri,
Claudio Cobelli,
Robert A. Rizza,
Adrian Vella
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-2561
Subject(s) - prediabetes , medicine , endocrinology , type 2 diabetes , glucagon like peptide 1 , insulin , glucose tolerance test , diabetes mellitus , glucagon , pathogenesis , impaired glucose tolerance , carbohydrate metabolism , insulin resistance
There has been much speculation as to whether defects in glucagon-like peptide-1 (GLP-1) secretion play a role in the pathogenesis of type 2 diabetes and the progression from normal glucose tolerance to prediabetes and diabetes.
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