Human Melatonin and Alerting Response to Blue-Enriched Light Depend on a Polymorphism in the Clock Gene PER3
Author(s) -
Sarah L. Chellappa,
Antoine Viola,
Christina Schmidt,
Valérie Bachmann,
Virginie Gabel,
Micheline Maire,
Carolin Reichert,
Amandine Valomon,
Thomas Götz,
HansPeter Landolt,
Christian Cajochen
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-2391
Subject(s) - melatonin , evening , endogeny , polymorphism (computer science) , endocrinology , alertness , allele , biology , medicine , circadian rhythm , context (archaeology) , genetics , gene , pharmacology , physics , paleontology , astronomy
Light exposure, particularly at the short-wavelength range, triggers several nonvisual responses in humans. However, the extent to which the melatonin-suppressing and alerting effect of light differs among individuals remains unknown.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom