Effects of Dapagliflozin on Body Weight, Total Fat Mass, and Regional Adipose Tissue Distribution in Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control on Metformin
Author(s) -
Jan Bolinder,
Östen Ljunggren,
Joel Kullberg,
Lars Johansson,
John Wilding,
Anna Maria Langkilde,
Jennifer Sugg,
Shamik Parikh
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-2260
Subject(s) - dapagliflozin , medicine , metformin , body mass index , endocrinology , adipose tissue , placebo , type 2 diabetes , weight loss , glycemic , waist , urology , diabetes mellitus , obesity , alternative medicine , pathology
Dapagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, reduces hyperglycemia in patients with type 2 diabetes mellitus (T2DM) by increasing urinary glucose excretion, and weight loss is a consistent associated finding.
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