Sclerostin and Its Association with Physical Activity, Age, Gender, Body Composition, and Bone Mineral Content in Healthy Adults | Zendy

Karin Amrein | Zendy; Steven Amrein | Zendy; Camilla Drexler | Zendy; Hans Peter Dimai | Zendy; Harald Dobnig | Zendy; Klaus Pfeifer | Zendy; Andreas Tomaschitz | Zendy; Thomas R. Pieber | Zendy; Astrid FahrleitnerPammer | Zendy

Open Access

Sclerostin and Its Association with Physical Activity, Age, Gender, Body Composition, and Bone Mineral Content in Healthy Adults

Author(s) -

Karin Amrein,

Steven Amrein,

Camilla Drexler,

Hans Peter Dimai,

Harald Dobnig,

Klaus Pfeifer,

Andreas Tomaschitz,

Thomas R. Pieber,

Astrid FahrleitnerPammer

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-2152

Subject(s) - sclerostin , osteocalcin , medicine , endocrinology , bone mineral , quartile , body mass index , physiology , alkaline phosphatase , wnt signaling pathway , chemistry , osteoporosis , confidence interval , biochemistry , gene , enzyme

Sclerostin is produced by osteocytes and inhibits bone formation through the Wnt/β-catenin-signaling pathway. Only limited data are available on circulating sclerostin levels in healthy subjects.

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