Proangiogenic Effect of TSH in Human Microvascular Endothelial Cells through Its Membrane Receptor | Zendy

Silvana Balzan | Zendy; R. Del Carratore | Zendy; Giuseppiicolini | Zendy; Pascale Beffy | Zendy; Valter Lubrano | Zendy; Francesca Forini | Zendy; Giorgio Iervasi | Zendy

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Proangiogenic Effect of TSH in Human Microvascular Endothelial Cells through Its Membrane Receptor

Author(s) -

Silvana Balzan,

R. Del Carratore,

Giuseppiicolini,

Pascale Beffy,

Valter Lubrano,

Francesca Forini,

Giorgio Iervasi

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-2146

Subject(s) - endocrinology , medicine , angiogenesis , matrigel , endothelial stem cell , receptor , biology , signal transduction , kinase insert domain receptor , vascular endothelial growth factor , vascular endothelial growth factor a , microbiology and biotechnology , biochemistry , in vitro , vegf receptors

TSH, which acts via specific cell membrane TSH receptors (TSHR), is regarded as a thyroid-specific growth factor. Recently, the presence of TSHR has been reported in extrathyroid tissues, but the role of TSH in nonthyroid tissue is unknown.

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