Loss of Enteroendocrine Cells in Autoimmune-Polyendocrine-Candidiasis-Ectodermal-Dystrophy (APECED) Syndrome with Gastrointestinal Dysfunction | Zendy

Carsten Posovszky | Zendy; Georgia Lahr | Zendy; Julia von Schnurbein | Zendy; Stephan Buderus | Zendy; Annette Findeisen | Zendy; Carmen Schröder | Zendy; CARL BRYANT SCHUTZ | Zendy; Anselm Schulz | Zendy; KlausMichael Debatin | Zendy; Martin Wabitsch | Zendy; Thomas F.E. Barth | Zendy

Open Access

Loss of Enteroendocrine Cells in Autoimmune-Polyendocrine-Candidiasis-Ectodermal-Dystrophy (APECED) Syndrome with Gastrointestinal Dysfunction

Author(s) -

Carsten Posovszky,

Georgia Lahr,

Julia von Schnurbein,

Stephan Buderus,

Annette Findeisen,

Carmen Schröder,

CARL BRYANT SCHUTZ,

Anselm Schulz,

KlausMichael Debatin,

Martin Wabitsch,

Thomas F.E. Barth

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-2044

Subject(s) - medicine , gastroenterology , enteroendocrine cell , chromogranin a , malabsorption , autoimmune gastritis , gastrointestinal disorder , irritable bowel syndrome , chronic mucocutaneous candidiasis , pathology , autoimmunity , disease , endocrine system , immunohistochemistry , hormone

Enteroendocrine (EE) cells are necessary for the regulation of gastrointestinal function. The lack of intestinal enteroendocrine cells in enteroendocrine cell dysgenesis causes severe malabsorptive diarrhea. Autoimmune-polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) is often accompanied by gastrointestinal (GI) symptoms.

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