Phospholipid Transfer Protein in the Placental Endothelium Is Affected by Gestational Diabetes Mellitus
Author(s) -
Monika Scholler,
Christian Wadsack,
Ingrid Lang,
Karoline Etschmaier,
Cornelia Schweinzer,
Gunther Marsche,
Martina DieberRotheneder,
Gernot Desoyé,
Ute Panzenboeck
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-1942
Subject(s) - phospholipid transfer protein , medicine , endocrinology , fetus , placenta , gestational diabetes , hyperinsulinemia , preeclampsia , insulin , biology , pregnancy , phospholipid , gestation , insulin resistance , biochemistry , genetics , membrane
Gestational diabetes mellitus (GDM) causes alterations in fetal high-density lipoproteins (HDL). Because phospholipid transfer protein (PLTP) is important for HDL (re)assembly and is expressed in the human placenta, we hypothesized that circulating fetal and/or placental PLTP expression and activity are altered in GDM.
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