Diagnostic Value of Salivary Cortisol in the CRH Stimulation Test in Premature Infants | Zendy

Takashi Matsukura | Zendy; Masahiko Kawai | Zendy; Chieko Marumo | Zendy; Kougoro Iwanaga | Zendy; Kayo Yoshida | Zendy; Minoru Shibata | Zendy; Fusako Niwa | Zendy; Takeshi Hasegawa | Zendy; Toshio Heike | Zendy

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Diagnostic Value of Salivary Cortisol in the CRH Stimulation Test in Premature Infants

Author(s) -

Takashi Matsukura,

Masahiko Kawai,

Chieko Marumo,

Kougoro Iwanaga,

Kayo Yoshida,

Minoru Shibata,

Fusako Niwa,

Takeshi Hasegawa,

Toshio Heike

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-1814

Subject(s) - saliva , medicine , endocrinology , gestational age , glucocorticoid , corticotropin releasing hormone , hydrocortisone , adrenal insufficiency , hormone , physiology , pregnancy , biology , genetics

According to a recent nationwide survey in Japan, a significant proportion of very low birth weight infants (VLBWI) develop late-onset circulatory collapse after the first week of life. Small doses of glucocorticoid are very effective in these patients, and relative adrenal insufficiency is suspected to be the main cause of the condition. Although the CRH test is required to evaluate the hypothalamic-pituitary-adrenal axis, obtaining multiple blood samples is invasive.

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