Effects of Aerobic Exercise Training on C1q Tumor Necrosis Factor α-Related Protein Isoform 5 (Myonectin): Association with Insulin Resistance and Mitochondrial DNA Density in Women
Author(s) -
Soo Lim,
Sung Hee Choi,
Bo Kyung Koo,
Seon Mee Kang,
Ji Won Yoon,
Hak Chul Jang,
Soon Mi Choi,
Man Gyoon Lee,
Wan Lee,
Hayley Shin,
YoungBum Kim,
Hong Kyu Lee,
Kyong Soo Park
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-1743
Subject(s) - insulin resistance , adiponectin , medicine , endocrinology , aerobic exercise , insulin , mitochondrial dna , homeostasis , vo2 max , biology , gene , genetics , blood pressure , heart rate
The C1q TNFα-related protein (C1QTNF) families exhibit a C-terminal complement factor C1q globular domain similar to that of TNF. However, their clinical implications are largely unknown. We recently found that the C1q TNFα-related protein isoform 5 (C1QTNF5 or myonectin) level was increased in insulin-resistant rodents and mitochondrial DNA (mtDNA)-depleted myocytes.
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