TheMC4R(I251L) Allele Is Associated with Better Metabolic Status and More Weight Loss after Gastric Bypass Surgery | Zendy

Uyenlinh L. Mirshahi | Zendy; Christopher D. Still | Zendy; Kathryn Masker | Zendy; Glenn S. Gerhard | Zendy; David J. Carey | Zendy; Tooraj Mirshahi | Zendy

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TheMC4R(I251L) Allele Is Associated with Better Metabolic Status and More Weight Loss after Gastric Bypass Surgery

Author(s) -

Uyenlinh L. Mirshahi,

Christopher D. Still,

Kathryn Masker,

Glenn S. Gerhard,

David J. Carey,

Tooraj Mirshahi

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-1549

Subject(s) - weight loss , allele , glucose homeostasis , medicine , obesity , diabetes mellitus , type 2 diabetes , genotype , endocrinology , insulin resistance , gastroenterology , physiology , biology , genetics , gene

Factors that influence long-term weight loss after Roux-en Y gastric bypass (RYGB) surgeries are poorly defined. The melanocortin system plays an important role in regulating energy homeostasis, satiety, and glucose metabolism. Variations of the MC4R comprise the most prevalent monogenetic obesity disorder.

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