Iron Modifies Plasma FGF23 Differently in Autosomal Dominant Hypophosphatemic Rickets and Healthy Humans | Zendy

Erik A. Imel | Zendy; Munro Peacock | Zendy; Amie K. Gray | Zendy; Leah R. Padgett | Zendy; Siu L. Hui | Zendy; Michael J. Econs | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Iron Modifies Plasma FGF23 Differently in Autosomal Dominant Hypophosphatemic Rickets and Healthy Humans

Author(s) -

Erik A. Imel,

Munro Peacock,

Amie K. Gray,

Leah R. Padgett,

Siu L. Hui,

Michael J. Econs

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-1239

Subject(s) - hypophosphatemia , hypophosphatemic rickets , fibroblast growth factor 23 , endocrinology , medicine , phosphate , rickets , chemistry , calcium , biochemistry , vitamin d and neurology , parathyroid hormone

In autosomal dominant hypophosphatemic rickets (ADHR), fibroblast growth factor 23 (FGF23) resists cleavage, causing increased plasma FGF23 levels. The clinical phenotype includes variable onset during childhood or adulthood and waxing/waning of hypophosphatemia. Delayed onset after puberty in females suggests iron status may be important.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research