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Stress is considered to be a major factor in the regulation of growth. Psychosocial dwarfism, characterized with short stature, delayed puberty, and depression, is typically preceded by psychological harassment or stressful environment. It has been observed that stress suppresses GH secretion, possibly via the attenuation of GHRH secretion. However, the exact mechanism of the impact of stress on growth has not been elucidated yet.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Catecholaminergic Axonal Varicosities Appear to Innervate Growth Hormone-Releasing Hormone-Immunoreactive Neurons in the Human Hypothalamus: The Possible Morphological Substrate of the Stress-Suppressed Growth