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Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis
Author(s) -
Sae Jeong Yang,
Soon Young Hwang,
Hee Youn Choi,
Hye Jin Yoo,
Ji A Seo,
Sin Gon Kim,
Nan Hee Kim,
Sei Hyun Baik,
Dong Seop Choi,
Kyung Mook Choi
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0620
Subject(s) - prediabetes , insulin resistance , selenoprotein p , medicine , type 2 diabetes , inflammation , diabetes mellitus , endocrinology , oxidative stress , catalase , glutathione peroxidase
The dysregulation of hepatokines may be associated with the pathogenesis of insulin resistance and type 2 diabetes. A recent study has suggested that selenoprotein P (SeP), a novel hepatokine, may play a role in the regulation of glucose metabolism and insulin sensitivity. We examined the relationship between circulating SeP levels and clinical parameters associated with insulin resistance in humans.

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