Differential Nongenetic Impact of Birth Weight Versus Third-Trimester Growth Velocity on Glucose Metabolism and Magnetic Resonance Imaging Abdominal Obesity in Young Healthy Twins | Zendy

Kasper Pilgaard | Zendy; Thomas Hammershaimb Mosbech | Zendy; Louise Groth Grunnet | Zendy; Hans Eiberg | Zendy; Gerrit van Hall | Zendy; Eva Fallentin | Zendy; Torben Larsen | Zendy; Rasmus Larsen | Zendy; Pernille Poulsen | Zendy; Allan Vaag | Zendy

Open Access

Differential Nongenetic Impact of Birth Weight Versus Third-Trimester Growth Velocity on Glucose Metabolism and Magnetic Resonance Imaging Abdominal Obesity in Young Healthy Twins

Author(s) -

Kasper Pilgaard,

Thomas Hammershaimb Mosbech,

Louise Groth Grunnet,

Hans Eiberg,

Gerrit van Hall,

Eva Fallentin,

Torben Larsen,

Rasmus Larsen,

Pernille Poulsen,

Allan Vaag

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-0577

Subject(s) - magnetic resonance imaging , obesity , abdominal obesity , medicine , endocrinology , birth weight , pregnancy , biology , metabolic syndrome , radiology , genetics

Low birth weight is associated with type 2 diabetes, which to some extent may be mediated via abdominal adiposity and insulin resistance. Fetal growth velocity is high during the third trimester, constituting a potential critical window for organ programming. Intra-pair differences among monozygotic twins are instrumental in determining nongenetic associations between early environment and adult metabolic phenotype.

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