Open AccessEarly Metformin Therapy (Age 8–12 Years) in Girls with Precocious Pubarche to Reduce Hirsutism, Androgen Excess, and Oligomenorrhea in Adolescence
Author(s) -
Lourdes Ibáñez,
Abel LópezBermejo,
Marta Díaz,
María Victoria Marcos,
Francis de Zegher
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0555
Subject(s) - hirsutism , polycystic ovary , androgen excess , medicine , metformin , androgen , endocrinology , menstrual cycle , precocious puberty , diabetes mellitus , obesity , insulin resistance , hormone
Girls with a combined history of low(-normal) birth weight (LBW) and precocious pubarche (PP) are at high risk to develop polycystic ovary syndrome (PCOS).
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