High Prevalence of Brown Adipose Tissue in Adult Humans
Author(s) -
Paul Lee,
Jing Zhao,
Michael M. Swarbrick,
Gary Gracie,
Ron Bova,
Jerry R. Greenfield,
Judith Freund,
Ken K. Y. Ho
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0487
Subject(s) - adipose tissue , brown adipose tissue , medicine , physiology , biology
Positron emission tomography (PET)-computed tomography (CT) has identified metabolically active supraclavicular fat in adult humans based on uptake of labeled glucose and confirmed to be brown adipose tissue (BAT) histologically. However, PET-CT has estimated a prevalence of BAT as low as 5% in adult humans, casting doubt on its significance. The true prevalence of BAT is unknown because of the suboptimal sensitivity of standard PET-CT.
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