Substitution of Standard Soybean Oil with Olive Oil-Based Lipid Emulsion in Parenteral Nutrition: Comparison of Vascular, Metabolic, and Inflammatory Effects
Author(s) -
Joselita Siqueira,
Dawn Smiley,
Christopher Newton,
NgocAnh Le,
Aidar R. Gosmanov,
Ronnie Spiegelman,
Limin Peng,
Samantha J. Osteen,
Dean P. Jones,
Arshed A. Quyyumi,
Thomas R. Ziegler,
Guillermo E. Umpierrez
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0480
Subject(s) - soybean oil , crossover study , saline , lipid profile , medicine , fish oil , polyunsaturated fatty acid , chemistry , proinflammatory cytokine , food science , endocrinology , biochemistry , fatty acid , inflammation , diabetes mellitus , biology , pathology , alternative medicine , fishery , fish <actinopterygii> , placebo
Soybean oil-based lipid emulsions are the only Food and Drug Administration-approved lipid formulation for clinical use in parenteral nutrition (PN). Recently concerns with its use have been raised due to the proinflammatory effects that may lead to increased complications because they are rich in ω-6 polyunsaturated fatty acids.
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