The Postoperative Basal Cortisol and CRH Tests for Prediction of Long-Term Remission from Cushing's Disease after Transsphenoidal Surgery | Zendy

John R. Lindsay | Zendy; Edward H. Oldfield | Zendy; Constantine A. Stratakis | Zendy; Lynnette K. Nieman | Zendy

Open Access

The Postoperative Basal Cortisol and CRH Tests for Prediction of Long-Term Remission from Cushing's Disease after Transsphenoidal Surgery

Author(s) -

John R. Lindsay,

Edward H. Oldfield,

Constantine A. Stratakis,

Lynnette K. Nieman

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-0456

Subject(s) - cushing's disease , transsphenoidal surgery , basal (medicine) , context (archaeology) , medicine , disease , cushing disease , surgery , cushing syndrome , endocrinology , adenoma , pituitary adenoma , biology , insulin , paleontology

Selective adenomectomy via transsphenoidal surgery induces remission of Cushing's disease (CD) in most patients. Although an undetectable postoperative serum cortisol (<2 μg/dl) has been advocated as an index of remission, there is no consensus on predictors of recurrence.

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